Starting route
Lyon to Italy
London → Lille → Lyon → Turin → Milan → Rome
Change from Eurostar to TGV at Lille and spend the night in Lyon. Continue on Frecciarossa through Turin to Milan, then take the onward service to Rome. The planner includes the Lyon stay; Turin is shown as part of the corridor.
Another way
A night in Paris
London → Paris → Turin → Milan → Rome
Use Paris as your first overnight stop, then head towards Milan. Allow for the transfer between the Eurostar arrival station and the Italian departure station. This is a different city break, not just a renamed version of the Lyon route.
Another way
Add Zürich
London → Paris → Zurich → Milan → Rome
Make Switzerland part of the trip with a stop in Zürich before Milan. Compare the extra connections and daily travel time. Pick this corridor when the intermediate stop matters to you as much as the final arrival.
Termini or Tiburtina?
Roma Termini is the central terminus, while Roma Tiburtina also serves high-speed trains. Check the station in the result against where you are staying. A train calling at Rome is not necessarily a train calling at Termini.
Choose your last travel day
On a multi-day trip, review the Milan connection together with your arrival in Rome. An earlier final arrival may be more useful than a shorter total trip with a late finish. Use the planner to compare both, then book with the operators.